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Former FDA chief Dr. David Kessler says the new weight-loss drugs are a powerful tool to fight obesity. But they come with pitfalls. Here's his tips for how to use them successfully.

NPR's Ayesha Rascoe plays the puzzle with KPCC listener Jerry Tsai and Weekend Edition Puzzlemaster Will Shortz.

Vienna has a way to make affordable housing and combat climate change all at the same time. Now U.S. cities want in, and they're building their own green housing.

Police responded after protesters tackled and restrained a man holding a long object and shouting at the crowd. Moments earlier, the man used the stick to smash the windows of a car he had been driving and stopped in the middle of the street.

Sheriff's deputies pronounced a Spencer man dead at the scene, and the other driver, identified as Cindy Bentley of Gosport, was seriously injured and transported by helicopter to Indianapolis for treatment.

The London-bound plane struck a medical college hostel in a residential area of the northwestern city of Ahmedabad minutes after takeoff Thursday, killing 241 on board and at least 29 on the ground.

People gathered for pro-democracy protests across the country today.

The town of Swannanoa is a mess after Helene. Some businesses may never reopen — including the only grocery store. "Swannanoa is a food desert," says the head of a nonprofit that brings in fresh food.

Israel's military says the nine nuclear scientists killed played spent decades working on Iran's nuclear program.

A lot happened this week, and NPR has you covered. Catch up on the big news and culture moments you might have missed.