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The designation comes from the World Organization for Animal Health, which requires confirmation that the virus has been eliminated from infected sites and that 28 days has passed without additional detections.
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The last reported case was at a commercial table egg pullet in Kosciusko County on March 28.
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In the letter, Sen. Todd Young and his colleagues ask for an aggressive vaccination strategy, new ways to combat the spread of disease, and movement controls for all at-risk animals.
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In a press release, global animal health company Zoetis announced that it received conditional approval from the USDA for a vaccine it developed for bird flu.
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Two flocks totaling 2.6 million birds have been infected and are under quarantine in Jay County. The farms in question have not been revealed publicly.
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About 912,000 egg-laying hens have been affected and are under quarantine in Jay County. The farm under quarantine has not been revealed publicly.
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The latest case, reported Wednesday, was a flock of 354,000 egg laying hens.
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While Indiana still has no reported cases, neighboring Michigan does.
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Laboratory testing of a second commercial duck flock in Elkhart County came back as presumptively positive for the virus, the Indiana State Board of Animal Health said.
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Laboratory testing of a second commercial flock of turkeys in Greene County has come back as presumptively positive for the virus, the Indiana State Board of Animal Health said.