© 2026. The Trustees of Indiana University
Copyright Complaints
1229 East Seventh Street, Bloomington, Indiana 47405
News, Arts and Culture from WFIU Public Radio and WTIU Public Television
Play Live Radio
Next Up:
0:00
0:00
0:00 0:00
Available On Air Stations

New Technique Helps Researchers Understand How Bacteria Become Antibiotic Resistant

Jennifer Chlebek explains how the imaging technique works and what she looks for while she is studying bacteria.
Jennifer Chlebek explains how the imaging technique works and what she looks for while she is studying bacteria.

Thanks to a new imaging technique invented at Indiana University, researchers are now able to watch parts and functions of bacteria that they couldn’t before.

Researchers can now watch bacteria’s tentacle-like appendages called, Pili, extend and retract, taking in DNA from its environment. This allows the bacteria to acquire new genetic traits and functions.

The process is how bacteria becomes resistant to antibiotics.

Jennifer Chlebek is a Ph.D. student who led the study. She says the new imaging technique allows a much better understanding of how the pili function.

“We thought for a long time we knew about how these motors worked," she says. "Trying to study them just a little bit further led us to uncover even one new mechanism of how these pili are dissembled. I think there's a lot more to be discovered just by studying them further and using this new technique."

Chlebek says understanding bacteria and how their pili function is key to disease prevention. Before the imaging technique invented by IU, researchers had to kill the cells to observe their structure.

She says the next step is to figure out more about how bacteria extend and retract their pili.

Bente Bouthier is a reporter and show producer with WFIU and WTIU News. She graduated from Indiana University in 2019, where she studied journalism, public affairs, and French.